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甲磺西泮

维基百科，自由的百科全书
甲磺西泮
识别信息
  • 7-chloro-5-(2-chlorophenyl)-1-[2-(4-methylphenyl)sulfonylethyl]-3H-1,4-benzodiazepin-2-one
CAS号86273-92-9  checkY
PubChem CID
ChemSpider
UNII
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)
化学信息
化学式C24H20Cl2N2O3S
摩尔质量487.40 g·mol−1
3D模型（JSmol（英语：JSmol））
  • Clc2ccccc2C(=NCC1=O)c3cc(Cl)ccc3N1CCS(=O)(=O)c(cc4)ccc4C
  • InChI=1S/C24H20Cl2N2O3S/c1-16-6-9-18(10-7-16)32(30,31)13-12-28-22-11-8-17(25)14-20(22)24(27-15-23(28)29)19-4-2-3-5-21(19)26/h2-11,14H,12-13,15H2,1H3 ☒N
  • Key:FFZOBTGTWSRRMB-UHFFFAOYSA-N ☒N

甲磺西泮（英语：Tolufazepam）是一种苯二氮䓬衍生物药物。[1]研究表明甲磺西泮对动物受试者具有抗惊厥和抗焦虑活性，[2]包括由戊四唑引起的惊厥。[3]

参见

参考文献

  1. ^ List of International Non-Proprietary Names (INNs), Provided for Pharmaceutical Substances by the World Health Organization, Which Are Free of Duty. Official Journal of the European Communities. 23 October 2001 [7 December 2009]. （原始内容 (PDF)存档于27 June 2014）. 
  2. ^ Hrib NJ, Martin LL. Chapter 2. Antianxiety Agents and Anticonvulsants. Annual Reports in Medicinal Chemistry 24. 1989: 11–20. ISBN 9780120405244. doi:10.1016/s0065-7743(08)60524-2. 
  3. ^ Pérez C, Mondelo N, Stéfano FJ, Lores Arnaiz J. Pharmacological activity of novel alkylsulfonylaryl-1-substituted-1,4-benzodiazepine derivatives. Archives Internationales de Pharmacodynamie et de Therapie. May 1988, 293: 57–68. PMID 2901826. 
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