跳至內容

阿巴諾喹

維基百科,自由的百科全書
阿巴諾喹
臨床資料
ATC碼
  • 未分配
識別資訊
  • 2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-6,7-dimethoxyquinolin-4-amine
CAS號90402-40-7
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
化學資訊
化學式C22H25N3O4
摩爾質量395.46 g·mol−1
3D模型(JSmol英語JSmol
  • COC1=C(C=C2CN(CCC2=C1)C3=NC4=CC(=C(C=C4C(=C3)N)OC)OC)OC
  • InChI=1S/C22H25N3O4/c1-26-18-7-13-5-6-25(12-14(13)8-19(18)27-2)22-10-16(23)15-9-20(28-3)21(29-4)11-17(15)24-22/h7-11H,5-6,12H2,1-4H3,(H2,23,24) checkY
  • Key:ANZIISNSHPKVRV-UHFFFAOYSA-N checkY

阿巴諾喹INN:abanoquil;開發代號:UK-52,046)是一種α1-腎上腺素能受體拮抗劑、抗心律失常藥物。[1]一項研究顯示阿巴諾喹可能可以用於治療勃起功能障礙[2]

參考資料

  1. ^ Tham TC, Guy S, Shanks RG, Harron DW. Dose-dependent alpha 1-adrenoceptor antagonist activity of the anti-arrhythmic drug, abanoquil (UK-52,046), without reduction in blood pressure in man. British Journal of Clinical Pharmacology. April 1992, 33 (4): 405–9. PMC 1381330可免費查閱. PMID 1349492. doi:10.1111/j.1365-2125.1992.tb04059.x. 
  2. ^ Giraldi, A.; Wyllie, M.; Wagner, G. Abanoquil, a new alpha-1 adrenoceptor antagonist. In vitro and in vivo effect on erectile tissue. International Journal of Impotence Research. 2000-03,. 12 Suppl 1 [2024-03-17]. ISSN 0955-9930. PMID 10845763. (原始內容存檔於2024-03-17).