CD90

CD90
識別號
別名	THY1；, CD90, CDw90, Thy-1 cell surface antigen
外部ID	OMIM：188230 MGI：98747 HomoloGene：4580 GeneCards：THY1
基因位置（人類）
染色體	11號染色體
終止	119,424,985 bp
基因位置（小鼠）
染色體	小鼠9號染色體
終止	43,959,876 bp
RNA表達模式
	; ; ; ;
	查閱更多表達數據
基因本體
分子功能	• 血漿蛋白結合; • 酶結合; • GPI anchor binding; • GTPase activator activity; • protein kinase binding; • integrin binding;
細胞組分	• 細胞質基質; • 膜; • 粘着斑; • 生長錐; • anchored component of plasma membrane; • integral component of plasma membrane; • apical plasma membrane; • 內質網; • anchored component of membrane; • 外排體; • external side of plasma membrane; • 脂筏模型; • anchored component of external side of plasma membrane; • 樹突; • myelin sheath; • 細胞外區域; • 細胞膜; • cell surface; • axolemma; • dendrite membrane; • neuronal cell body membrane;
生物學過程	• negative regulation of T cell receptor signaling pathway; • positive regulation of GTPase activity; • 自體磷酸化; • negative regulation of protein kinase activity; • 細胞粘附; • negative regulation of cell migration; • 血管新生; • negative regulation of axonogenesis; • 細胞骨架組織; • regulation of cell migration; • positive regulation of T cell activation; • T cell receptor signaling pathway; • retinal cone cell development; • positive regulation of release of sequestered calcium ion into cytosol; • C-terminal protein lipidation; • regulation of cell-matrix adhesion; • positive regulation of cellular extravasation; • integrin-mediated signaling pathway; • cell-cell signaling; • positive regulation of heterotypic cell-cell adhesion; • receptor clustering; • positive regulation of focal adhesion assembly; • negative regulation of protein tyrosine kinase activity; • negative regulation of neuron projection regeneration; • regulation of Rho-dependent protein serine/threonine kinase activity; • focal adhesion assembly; • cell-cell adhesion;
	Sources:Amigo / QuickGO
直系同源
	7070
	21838
	ENSG00000154096
	ENSMUSG00000032011
	P04216
	P01831
	NM_006288; NM_001311160; NM_001311162; NM_001372050
	NM_009382
	NP_001298089; NP_001298091; NP_006279; NP_001358979
	NP_033408
	維基數據
檢視/編輯人類	檢視/編輯小鼠

Thy-1 或 CD90（Cluster of Differentiation 90，分化簇90）是一個25-37kDa重度N-糖基化的細胞表面蛋白質，通過C-末端的糖磷脂酰肌醇（glycophosphatidylinositol，GPI）錨定到細胞膜外側。CD90最初作為一個胸腺細胞的表面抗原發現，故最早稱為Thy-1。此後，Thy-1不斷在各種幹細胞和軸突分化成熟的的神經元上發現，現在更傾向於稱作CD90。CD90帶有一個V型的免疫球蛋白結構域，是免疫球蛋白超家族的一員，幾乎是其中分子量最小的成員。

參考文獻

^ ^1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000154096 - Ensembl, May 2017
^ ^2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000032011 - Ensembl, May 2017
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

外部連結

Human THY1 genome location and THY1 gene details page in the UCSC Genome Browser（英語：UCSC Genome Browser）.

[refGRCh38Ensembl-1] 1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000154096 - Ensembl, May 2017

[refGRCm38Ensembl-2] 2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000032011 - Ensembl, May 2017

[3] Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

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