跳转到内容

钩藤碱

维基百科,自由的百科全书
钩藤碱
Chemical structure of rhynchophylline
IUPAC名
Methyl (7R,16E)-17-methoxy-2-oxo-16,17-didehydro-20α-corynoxan-16-carboxylate
系统名
Methyl (2E)-2-[(1′R,6′R,7′S,8a′S)-6′-ethyl-2-oxo-1,2,2′,3′,6′,7′,8′,8a′-octahydro-5′H-spiro[indole-3,1′-indolizin]-7′-yl]-3-methoxyprop-2-enoate
别名
  • Rhyncophylline
  • Mitrinermin
  • Mitrinermine
  • Rhynchophyllin
  • Rhynocophylline
识别
CAS号 76-66-4  checkY
PubChem 3033948
ChemSpider 4444758
SMILES
 
  • CC[C@H]1CN2CC[C@]3([C@@H]2C[C@@H]1/C(=C\OC)/C(=O)OC)C4=CC=CC=C4NC3=O
InChI
 
  • 1/C22H28N2O4/c1-4-14-12-24-10-9-22(17-7-5-6-8-18(17)23-21(22)26)19(24)11-15(14)16(13-27-2)20(25)28-3/h5-8,13-15,19H,4,9-12H2,1-3H3,(H,23,26)/b16-13+/t14-,15-,19-,22+/m0/s1
InChIKey DAXYUDFNWXHGBE-KAXDATADBC
ChEBI 70069
KEGG C09236
性质
化学式 C22H28N2O4
摩尔质量 384.47 g·mol−1
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

钩藤碱(英语:Rhynchophylline)是一种含氮有机化合物,化学式C22H28N2O4,是钩藤属植物,如钩藤Uncaria tomentosa[1]嘴叶钩藤Uncaria rhynchophylla[2]中提取的活性生物碱,也存在于卡痛树Mitragyna speciosa)的叶子[3]

参考文献

  1. ^ Mohamed AF, Matsumoto K, Tabata K, Takayama H, Kitajima M, Watanabe H. Effects of Uncaria tomentosa Total Alkaloid and its Components on Experimental Amnesia in Mice: Elucidation Using the Passive Avoidance Test. Journal of Pharmacy and Pharmacology. 2000, 52 (12): 1553–1561. PMID 11197086. S2CID 40280160. doi:10.1211/0022357001777612可免费查阅. 
  2. ^ Shi JS, Yu JX, Chen XP, Xu RX. Pharmacological Actions of Uncaria Alkaloids, Rhynchophylline and Isorhynchophylline (PDF). Acta Pharmacologica Sinica. 2003, 24 (2): 97–101. PMID 12546715. 
  3. ^ Mitragyna Speciosa (Kratom) - World Roots. 

外部链接