奥卡西平
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臨床資料 | |
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读音 | /ɒks.kɑːrˈbæz.ɪˌpiːn/ |
商品名 | Trileptal, Oxtellar XR, others |
AHFS/Drugs.com | Monograph |
MedlinePlus | a601245 |
核准狀況 | |
懷孕分級 |
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给药途径 | 口服给药 |
ATC碼 | |
法律規範狀態 | |
法律規範 |
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藥物動力學數據 | |
生物利用度 | >95% |
药物代谢 | Liver (cytosolic enzymes and glucuronic acid) |
生物半衰期 | 1–5 hours (healthy adults) |
排泄途徑 | Kidney (<1%)[1] |
识别信息 | |
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CAS号 | 28721-07-5 ![]() |
PubChem CID | |
IUPHAR/BPS | |
DrugBank | |
ChemSpider | |
UNII | |
KEGG | |
ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.044.702 |
化学信息 | |
化学式 | C15H12N2O2 |
摩尔质量 | 252.27 g·mol−1 |
3D模型(JSmol) | |
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奥卡西平(英語:Oxcarbazepine,商品名:Trileptal等)是一种含氮有机化合物,分子式C15H12N2O2,可作为抗癫痫药物[1],在体内的活性代謝產物为利卡西平[4]。
参考文献
- ^ 1.0 1.1 1.2 Trileptal- oxcarbazepine tablet, film coated Trileptal- oxcarbazepine suspension. DailyMed. [9 November 2020].
- ^ List of nationally authorised medicinal products : Active substance: oxcarbazepine : Procedure no.: PSUSA/00002235/202108 (PDF). Ema.europa.eu. [5 June 2022].
- ^ Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control]. Diário Oficial da União. 31 March 2023 (4 April 2023) [16 August 2023]. (原始内容存档于3 August 2023) (巴西葡萄牙语).
- ^ Oxcarbazepine Monograph for Professionals. Drugs.com. American Society of Health-System Pharmacists. [13 April 2019].
外部链接
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