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COLO 205

维基百科,自由的百科全书

COLO 205(亦稱ATCC CCL-222)是人類結腸癌細胞系[1],最初於1957年分離自一名70歲的白人男性結腸癌患者腹水,該患者已接受5-氟尿嘧啶治療數週[2]。有研究指出COLO 205的標記染色體英语Marker chromosomeCOLO 201相同,並且發現在COLO 205及COLO 201細胞中出現的等臂染色體英语Isochromosome5在COLO 206細胞中不存在[2]。目前應用於細胞毒性測定和免疫球蛋白表徵的免疫學研究[2]

參考資料

  1. ^ Björk, P; Jönsson, U; Svedberg, H; Larsson, K; Lind, P; Dillner, J; Hedlund, G; Dohlsten, M; Kalland, T. Isolation, partial characterization, and molecular cloning of a human colon adenocarcinoma cell-surface glycoprotein recognized by the C215 mouse monoclonal antibody.. The Journal of biological chemistry. 1993-11-15, 268 (32): 24232–41 [2019-12-09]. PMID 7693697. 
  2. ^ 2.0 2.1 2.2 Semple, TU; Quinn, LA; Woods, LK; Moore, GE. Tumor and lymphoid cell lines from a patient with carcinoma of the colon for a cytotoxicity model.. Cancer research. 1978-05, 38 (5): 1345–55 [2019-12-09]. PMID 565251. 

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