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CYP11C1

維基百科,自由的百科全書
cytochrome P450, family 11, subfamily c, polypeptide 1
標識
生物 Danio rerio
符號 CYP11C1
Entrez 791124
RefSeq (mRNA) NM_001080204.1
RefSeq (蛋白質) NP_001073673.1
UniProt A1XRK1
其他數據
EC number 1.14.15.4
染色體 16: 54.46 - 54.48 Mb

Cyp11c1魚類的一種編碼CYP450單加氧酶基因,最早發現於模式動物斑馬魚(學名:Danio rerio),負責催化皮質醇11-酮睪酮(11-KT)的形成[1][2],11-KT是斑馬魚的內源性雄激素

參考文獻 

  1. ^ Zhang Q, Ye D, Wang H, Wang Y, Hu W, Sun Y. Zebrafish cyp11c1 Knockout Reveals the Roles of 11-ketotestosterone and Cortisol in Sexual Development and Reproduction. Endocrinology. June 2020, 161 (6). PMID 32222764. doi:10.1210/endocr/bqaa048. 
  2. ^ Zheng Q, Xiao H, Shi H, Wang T, Sun L, Tao W, et al. Loss of Cyp11c1 causes delayed spermatogenesis due to the absence of 11-ketotestosterone. The Journal of Endocrinology. March 2020, 244 (3): 487–499. PMID 31910154. doi:10.1530/JOE-19-0438.