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CP 55,244

維基百科,自由的百科全書
CP 55,244
識別資訊
  • (2S,4S,4aS,6R,8aR)-6-(Hydroxymethyl)-4-[2-hydroxy-4-(2-methyloctan-2-yl)phenyl]-1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalen-2-ol
CAS號79678-32-3  checkY
PubChem CID
ChemSpider
UNII
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
化學資訊
化學式C26H42O3
摩爾質量402.62 g·mol−1
3D模型(JSmol英語JSmol
  • CCCCCCC(C)(C)c1ccc(c(c1)O)[C@H]2C[C@H](C[C@@H]3[C@@H]2C[C@@H](CC3)CO)O
  • InChI=1S/C26H42O3/c1-4-5-6-7-12-26(2,3)20-10-11-22(25(29)15-20)24-16-21(28)14-19-9-8-18(17-27)13-23(19)24/h10-11,15,18-19,21,23-24,27-29H,4-9,12-14,16-17H2,1-3H3/t18-,19-,21+,23+,24-/m1/s1
  • Key:ZAELPWSCABXXAB-QXASVXAKSA-N

CP 55,244是一種有機化合物,分子式C26H42O3,屬於人工合成的大麻素,具有鎮痛藥功能,由輝瑞公司開發[1],其對CB1的激動劑效果比HU-210更強[2]

另見

參考文獻

  1. ^ Melvin LS, Milne GM, Johnson MR, Wilken GH, Howlett AC. Structure-activity relationships defining the ACD-tricyclic cannabinoids: cannabinoid receptor binding and analgesic activity. Drug Design and Discovery. November 1995, 13 (2): 155–66. PMID 8872458. 
  2. ^ Griffin G, Wray EJ, Martin BR, Abood ME. Cannabinoid agonists and antagonists discriminated by receptor binding in rat cerebellum. British Journal of Pharmacology. October 1999, 128 (3): 684–8. PMC 1571656可免費查閱. PMID 10516649. doi:10.1038/sj.bjp.0702806. 

外部連結