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N-甲基猪毛菜酚

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N-甲基猪毛菜酚
识别
CAS号 53622-85-8  checkY
PubChem 124148
SMILES
 
  • C[C@H]1C=2C(=CC(O)=C(O)C2)CCN1C
ChEBI 88540
性质
化学式 C11H15NO2
摩尔质量 193.24 g·mol−1
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

N-甲基猪毛菜酚(英语:N-Methylsalsolinol)是一种有机化合物,化学式为C11H15NO2,具有很强的神经毒性[1]。它可由脱氧肾上腺素乙醛在催化下反应制得[2]。它存在RS异构体,其异构体可以通过高效液相色谱法进行分离[3]

参考文献

  1. ^ Quan, Zhe; Song, Yaru; Peters, Gladys; Shenwu, Ming; Sheng, Yinghong; Hwang, Huey-Min; Liu, Yi-Ming. Chiral CE Separation of Dopamine-Derived Neurotoxins. Analytical Sciences. 2005-02, 21 (2): 115–119. doi:10.2116/analsci.21.115. 
  2. ^ Ohla, Stefan; Beyreiss, Reinhild; Fritzsche, Stefanie; Glaser, Petra; Nagl, Stefan; Stockhausen, Kai; Schneider, Christoph; Belder, Detlev. Monitoring On‐Chip Pictet–Spengler Reactions by Integrated Analytical Separation and Label‐Free Time‐Resolved Fluorescence. Chemistry – A European Journal. 2012-01-23, 18 (4): 1240–1246. doi:10.1002/chem.201101768. 
  3. ^ Deng, Yulin; Maruyama, Wakako; Dostert, Philippe; Takahashi, Tsutomu; Kawai, Masao; Naoi, Makoto. Determination of the (R)- and (S)-enantiomers of salsolinol and N-methylsalsolinol by use of a chiral high-performance liquid chromatographic column. Journal of Chromatography B: Biomedical Sciences and Applications. 1995-08, 670 (1): 47–54. doi:10.1016/0378-4347(95)00136-7.