L1210细胞
L1210细胞系（Leukemia 1210）是来源于8个月大的雌性DBA/2近交系小鼠腹水的细胞系，为白血病淋巴细胞[1]。相比B淋巴细胞，L1210在形态上更接近淋巴母细胞，可在无胸腺裸鼠注入后7至10天发展成肿瘤[2]。尾静脉注射、腹腔注射或皮下接种L1210细胞可制备白血病小鼠模型[3][4]。有研究指出可以通过睾丸接种L1210细胞，制备小鼠白血病细胞睾丸浸润模型[5]
参考文献
- ^ Moore GE, Sandberg AA, Ulrich K. Suspension cell culture and in vivo and in vitro chromosome constitution of mouse leukemia L1210. J. Natl. Cancer Inst. 1960, 36 (3): 405–421. PMID 18630317. doi:10.1093/jnci/36.3.405.
- ^ L1210. [15 July 2018]. （原始内容存档于2019-10-06）.
- ^ Kozar, K; Kamiński, R; Switaj, T; Ołdak, T; Machaj, E; Wysocki, PJ; Mackiewicz, A; Lasek, W; Jakóbisiak, M; Gołab, J. Interleukin 12-based immunotherapy improves the antitumor effectiveness of a low-dose 5-Aza-2'-deoxycitidine treatment in L1210 leukemia and B16F10 melanoma models in mice.. Clinical cancer research : an official journal of the American Association for Cancer Research. 2003-08-01, 9 (8): 3124–33 [2019-11-23]. PMID 12912964.
- ^ Canti, G; Franco, P; Marelli, O; Ricci, L; Nicolin, A. Hematoporphyrin derivative rescue from toxicity caused by chemotherapy or radiation in a murine leukemia model (L1210).. Cancer research. 1984-04, 44 (4): 1551–6 [2019-11-23]. PMID 6231100.
- ^ Pouillart, P; Huong, TH; Lhéritier, J. [L 1210 leukemia, an experimental model for the potentiation of drugs used for acute leukemias].. Bulletin du cancer. NaN, 61 (4): 509–26 [2019-11-23]. PMID 4458834.
外部链接
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