2-异氰基丙烷
| 2-异氰基丙烷 | |
|---|---|
| |
| 英文名 | 2-isocyanopropane |
| 别名 | 异丙基异氰化物 |
| 识别 | |
| CAS号 | 598-45-8 
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| SMILES |
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| 性质 | |
| 化学式 | C4H7N |
| 摩尔质量 | 69.11 g·mol−1 |
| 外观 | 无色恶臭液体[1] |
| 沸点 | 85—87 °C（358—360 K）[2] |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
2-异氰基丙烷是一种有机化合物，化学式为C4H7N，它是异丁腈的同分异构体。它可由异丙胺和三氯甲烷在氢氧化钠和季铵盐的存在下在溶剂中反应得到[3]，N-异丙基甲酰胺和三氯氧磷在三乙胺的存在下于二氯甲烷中反应，也可得到2-异氰基丙烷。[1]它可作为配体和金属形成配合物。[4]
参考文献
- ^ 1.0 1.1 Lijie Wang, Jamie Ferguson, Fanlong Zeng. Palladium-catalyzed direct coupling of 2-vinylanilines and isocyanides: an efficient synthesis of 2-aminoquinolines. Organic & Biomolecular Chemistry. 2015, 13 (47): 11486–11491 [2021-04-07]. ISSN 1477-0520. doi:10.1039/C5OB01659B （英语）.
- ^ Henry Feuer, Harry Rubinstein, Arnold T. Nielsen. Reaction of Alkyl Isocyanides with Ozone. A New Isocyanate Synthesis 1. The Journal of Organic Chemistry. 1958-08, 23 (8): 1107–1109 [2021-04-07]. ISSN 0022-3263. doi:10.1021/jo01102a005 （英语）.
- ^ Debin Zeng, Yuying Ma, Rui Zhang, Quandeng Nie, Zhengjie Cui, Yaxin Wang, Luqing Shang, Zheng Yin. Synthesis and structure–activity relationship of α-keto amides as enterovirus 71 3C protease inhibitors. Bioorganic & Medicinal Chemistry Letters. 2016-04, 26 (7): 1762–1766 [2021-04-07]. doi:10.1016/j.bmcl.2016.02.039. （原始内容存档于2018-06-23） （英语）.
- ^ Belén Alvarez, M. Angeles Alvarez, M. Esther García, Daniel García-Vivó, Miguel A. Ruiz. C−C and C−N Couplings Following Hydride Addition on Isocyanide Cyclopolyenyl Dimolybdenum Complexes to Give Tethered Aldimine and Aminocarbene Derivatives. Chemistry - A European Journal. 2017-10-09, 23 (56): 14027–14038 [2021-04-07]. doi:10.1002/chem.201702998 （英语）.