雪腐镰刀菌烯醇
Nivalenol (NIV) | |
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别名 | (3α,4β,7α)-12,13-epoxy-3,4,7,15-tetrahydroxy-trichothec-9-en-8-one[1] |
识别 | |
CAS号 | 23282-20-4 ![]() |
PubChem | 31829 |
ChemSpider | 29515 |
SMILES |
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InChI |
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ChEBI | 7599 |
KEGG | C06080 |
性质 | |
化学式 | C15H20O7 |
摩尔质量 | 312.32 g·mol−1 |
外观 | solid |
密度 | 1.6±0.1 g/cm3 |
熔点 | 222-223 °C(272 K) |
沸点 | 585.1±50 °C |
溶解性(水) | 3.54*10^5 mg/L at 25 °C |
溶解性 | soluble in polar organic solvents |
pKa | 11.78 |
危险性 | |
GHS危险性符号![]() ![]() ![]() | |
GHS提示词 | Danger |
H-术语 | H225, H300, H302, H312, H332, H310, H319, H330 |
P-术语 | P210, P241, P260, P262, P264, P270, P271, P280, P284, P301+310, P302+350, P304+340, P310, P320 |
NFPA 704 | |
PEL | 40 ppm (70 mg/m3) [2] |
TLV | 20 ppm (34 mg/m3) Skin [2] |
致死量或浓度: | |
LD50(中位剂量)
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19.5 mg/kg (rats, oral), 38.9 mg/kg (mouse, oral) |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
雪腐镰刀菌烯醇(英语:Nivalenol,也译为:瓜萎镰菌醇,缩写NIV)是一种单端孢霉烯类霉菌毒素,化学式C15H20O7,主要在镰孢菌属(学名:Fusarium)真菌中发现[2][3]。
参考文献
- ^ 1.0 1.1 Nivalenol. Cayman Chemical. [28 March 2018]. (原始内容存档于2022-08-05).
- ^ 2.0 2.1 2.2 Nivalenol (PDF). Safety Data Sheet. [28 March 2018]. (原始内容存档 (PDF)于2021-08-20).
- ^ Scientific Opinion on risks for animal and public health related to the presence of nivalenol in food and feed. European Food Safety Authority (EFSA) Journal. 2013, 11 (6): 1–5.