洗滌紅細胞
洗滌紅細胞是指已經去除了大部分血漿、血小板和白細胞,並用生理鹽水或其他類型的保存溶液替代的紅細胞。[1][2] 在醫療輸血中,使用洗滌紅細胞通常是為了防止對藥物治療無反應的嚴重過敏性輸血反應的復發。這些過敏反應通常由供體血漿中的蛋白質導致,通過洗滌紅細胞的過程可以去除這些蛋白質。[3]使用洗滌紅細胞也降低了儲存期間紅細胞上清液中積累的鉀濃度,可作為在有高鉀血症風險的患者中輸注新鮮紅細胞的替代方法。[4]
參考文獻
- ^ Albiston B. Guideline for Washed Red Blood Cells in Nova Scotia (PDF). Nova Scotia. October 2011.
- ^ Lu M, Lezzar DL, Vörös E, Shevkoplyas SS. Traditional and emerging technologies for washing and volume reducing blood products. Journal of Blood Medicine. 2019, 10: 37–46. PMC 6322496 . PMID 30655711. doi:10.2147/JBM.S166316 .
- ^ Hirayama, Fumiya. Current understanding of allergic transfusion reactions: incidence, pathogenesis, laboratory tests, prevention and treatment. British Journal of Haematology. 2013-02, 160 (4) [2024-07-02]. ISSN 0007-1048. PMC 3594969 . PMID 23215650. doi:10.1111/bjh.12150. (原始內容存檔於2023-10-27) (英語).
- ^ Cardigan, Rebecca; New, Helen V.; Tinegate, Hazel; Thomas, Stephen. Washed red cells: theory and practice. Vox Sanguinis. 2020-11, 115 (8): 606–616. doi:10.1111/vox.12971.