國際癌症研究機構二B類致癌物
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2B類致癌物(英語:Group 2B carcinogens),為國際癌症研究機構對致癌物質的分類,此類物質(或其混合物)可能對人類致癌。截至2024年5月2日,共用323種[1]2B類致癌物(如黃樟素、四氯化碳、電磁波、抗甲狀腺藥物丙硫氧嘧啶、二異氰酸甲苯、抗愛滋病藥物齊多夫定、汽油引擎廢氣、乾洗業等),對人類為有可能致癌物,對動物為很可能也是致癌物。[2]更多詳細信息,可以搜尋國際癌症研究機構(IARC)專著。[3]
物質和物質組合
中文名稱 | 學名 | CAS號 | 歐盟委員會編號 EINECS |
備考 |
---|---|---|---|---|
A-a-C (2-Amino-9H-pyrido[2,3-b]indole) | US Biological 化學試藥類 | |||
乙醛 | Acetaldehyde | 0 | ||
乙酰胺 | Acetamide | 0 | ||
Acétate de médroxyprogestérone | 0 | |||
Acétate de méthylazoxyméthanol | 0 | |||
乙酸乙烯酯 | Acétate de vinyle | 0 | ||
咖啡酸 | Acide caféique | 0 | ||
Acide chlorendique | 0 | |||
二氯乙酸 | 0 | |||
氨三乙酸 | 0 | |||
Acrylate d'éthyle | 0 | |||
丙烯腈 | Acrylonitrile | 0 | ||
阿達帕林 | Adapalene | |||
AF-2 | Furylfuramide 2-(2-Furyl)-3-(5-nitro-2-furyl)acrylamide |
硝基蚨喃類殺菌劑,結構類似對羥基苯甲酸酯 | ||
黃麴毒素 M1 | Aflatoxin,M1 | 2 | ||
對-氨基偶氮苯 | Aniline Yellow para-Aminoazobenzene |
0 | 苯胺黃 | |
鄰-氨基偶氮甲苯 | ortho-Aminoazotoluene | 0 | 蘇丹紅IV代謝生成的物質 | |
2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole | 1 | |||
胺苯吖啶 | Amsacrine | 5 | 抗腫瘤藥,別名安丫啶、安吖啶 | |
鄰氨基苯甲醚 | ortho-Anisidine | 0 | ||
三氧化二銻 | Antimony trioxide | 1 | ||
異黃樟 | Aramite | 別名殺蟎特;異黃樟;殺蟎劑 | ||
金胺O | Auramine | 0 | 工業級(technical-grade) | |
重氮乙酰絲氨酸 | Azaserine | 0 | 別名氮絲氨酸;氮雜絲氨酸;重氮絲氨酸 - 用以抑制某些腫瘤生長的抗生素 | |
氮丙環 | Aziridine | 0 | ||
Benz[j]aceanthrylene | (多環芳香烴,PAHs) | |||
Benz(''a'')anthracene | 0 | (多環芳香烴,PAHs) | ||
Benzo(b)fluoranthene | 0 | (多環芳香烴,PAHs) | ||
Benzo(j)fluoranthene | 0 | (多環芳香烴,PAHs) | ||
Benzo(k)fluoranthene | 0 | (多環芳香烴,PAHs) | ||
Benzo(''c'')phenanthrene | 0 | (多環芳香烴,PAHs) | ||
苯並呋喃 | Benzofurane、Benzofuran | 0 | (多環芳香烴,PAHs) | |
Benzyl violet 4B 酸性紫4B |
紫色1號,C39H40N3NaO6S2,3-[[Ethyl[4-[[4-(dimethyliminio)-2,5-cyclohexadiene-1-ylidene][4-[ethyl[3-(sodiooxysulfonyl)benzyl]amino]phenyl]methyl]phenyl]amino]methyl]benzenesulfonate | 1 | 主要用於羊毛、絲綢、錦綸的染色[4] | |
二溴新戊醇 2,2-雙(溴甲基)-1,3-丙二醇 |
2,2-Bis(bromomethyl)propane-1,3-diol | 2 | 中間體或阻燃劑[5][6] | |
博來黴素 | Bleomycin | |||
Bracken fern | 蕨類植物;[7][8][9] | |||
溴二氯甲烷 | Bromodichloromethane | 0 | ||
丁基羥基茴香醚 | Butylated hydroxyanisole | 4 | ||
β-丁內酯 | b-Butyrolactone,別名4-甲基-β-丙酰內酯;B-丁內酯;Β-丁內酮,分子式為C4H6O2 | 2 | 酯類,可作單體[10][11] | |
碳煙 | Carbon black | |||
四氯化碳 | Carbon tetrachloride | |||
鄰苯二酚 | Catechol | |||
氯丹 | Chlordane | |||
十氯酮 | (開蓬,殺蟲﹑殺真菌藥,原商標名) | |||
氯菌酸 | 六氯內-甲烯基-四氫苯二甲酸 | 毒性「氣喘、肺水腫、過敏性皮膚炎、灼熱疼痛感,視線模糊並流淚」 | ||
4-氯苯胺 | para-Chloroaniline | 0 | ||
3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone | ||||
氯仿 | ||||
1-Chloro-2-methylpropene | ||||
Chlorophenoxy herbicides | ||||
4-Chloro-ortho-phenylenediamine | ||||
氯丁二烯 | ||||
百菌清 | ||||
䓛 | ||||
CI Acid Red 114 | ||||
副玫瑰苯胺 | ||||
CI Direct Blue 15 | ||||
Citrus Red 2 | ||||
鈷以及鈷化合物 | ||||
Cobalt sulfate and other soluble cobalt(II) salts | ||||
Cocamide DEA condensate | ||||
para-Cresidine | ||||
蘇鐵素 | ||||
達卡巴嗪 | ||||
丹蒽醌 (Chrysazin, 1,8-Dihydroxyanthraquinone) | ||||
道諾黴素 | ||||
滴滴涕 (p,p'-DDT) | ||||
N,N'-Diacetylbenzidine | ||||
2,4-Diaminoanisole | ||||
4,4'-二氨基二苯醚 | ||||
2,4-Diaminotoluene | ||||
Dibenz[a,h]acridine | ||||
Dibenz[a,j]acridine | ||||
7H-Dibenzo[c,g]carbazole | ||||
Dibenzo[a,e]pyrene | ||||
Dibenzo[a,h]pyrene | ||||
Dibenzo[a,i]pyrene | ||||
1,2-二溴-3-氯丙烷 | ||||
2,3-Dibromopropan-1-ol | ||||
二氯乙酸 | ||||
對二氯苯 | ||||
3,3'-Dichlorobenzidine | ||||
3,3'-Dichloro-4,4'-diaminodiphenyl ether | ||||
1,2-二氯乙烷 | ||||
二氯甲烷 (methylene chloride) | ||||
1,3-Dichloropropene (technical grade) | ||||
敵敵畏 | ||||
1,2-Diethylhydrazine | ||||
Diglycidyl resorcinol ether | ||||
Dihydrosafrole |
- Diisopropyl sulfate
- 3,3'-Dimethoxybenzidine (o-Dianisidine)
- 甲基黃
- trans-2-[(Dimethylamino)methylimino]-5-[2-(5-nitro-2-furyl)-vinyl]-1,3,4-oxadiazole
- 2,6-Xylidine (2,6-Dimethylaniline)
- 3,3'-Dimethylbenzidine (o-Tolidine)
- 偏二甲肼
- 3,7-Dinitrofluoranthene
- 3,9-Dinitrofluoranthene
- 1,6-Dinitropyrene
- 1,8-Dinitropyrene
- 2,4-二硝基甲苯
- 二硝基甲苯
- 1,4-二噁烷
- Disperse Blue 1
- 1,2-環氧丁烷
- 丙烯酸乙酯
- 乙苯
- 1,2-二氯乙烷
- 甲磺酸乙酯
- Foreign bodies, implanted in tissues
- Polymeric, prepared as thin smooth films (with the exception of poly(glycolic acid))
- Metallic, prepared as thin smooth films
- Metallic cobalt, metallic nickel and an alloy powder containing 66-67% nickel, 13-16% chromium and 7% iron
- 2-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazole
- Fumonisin B1
- 呋喃
- Glu-P-1 (2-Amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole)
- Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole)
- Glycidaldehyde
- 灰黃黴素
- HC Blue No. 1
- 七氯
- 六氯苯
- 六氯乙烷
- 六氯環己烷s
- 六甲基磷酰胺 (HMPA)
- 人類免疫缺陷病毒 type 2 (infection with)
- 人類乳突病毒es: some types other than 16, 18, 31 and 33
- 聯氨
- 1-Hydroxyanthraquinone
- Indeno[1,2,3-cd]pyrene
- Iron-dextran complex
- 異戊二烯
- 紫花果芸香鹼
- 鉛
- 磁場s (極低頻)
- MeA-a-C (2-Amino-3-methyl-9H-pyrido[2,3-b]indole)
- Medroxyprogesterone acetate
- MeIQ (2-Amino-3,4-dimethylimidazo[4,5-f]quinoline)
- MeIQx (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline)
- Merphalan
- 丙烯亞胺 (Propyleneimine)
- Methylazoxymethanol acetate
- 5-Methylchrysene
- 4,4'-Methylene bis(2-methylaniline)
- 4,4'-Methylenedianiline
- Methylmercury compounds
- 2-Methyl-1-nitroanthraquinone (uncertain purity)
- N-Methyl-N-nitrosourethane
- Methylthiouracil
- 甲硝唑
- Michler's base (4,4'-methylene-bis(N,N-dimethyl)benzenamine)
- 米氏酮 (4,4'-bis(dimethylamino)benzophenone)
- Microcystin-LR
- 滅蟻樂
- 絲裂黴素C
- 米托蒽醌
- 野百合鹼
- 5-(Morpholinomethyl)-3-[(5-nitrofurfurylidene)amino]-2-oxazolidinone
- 萘酚平
- 萘
- 鎳, metallic and alloys
- Niridazole
- 氨三乙酸 and its salts
- 5-Nitroacenaphthene
- 2-Nitroanisole
- 硝基苯
- 6-Nitrochrysene
- 護谷 (technical-grade)
- 2-Nitrofluorene
- 1-[(5-Nitrofurfurylidene)amino]-2-imidazolidinone
- N-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide
- Nitrogen mustard N-oxide
- 硝基甲烷
- 2-硝基丙烷
- 1-硝基芘
- 4-Nitropyrene
- N-Nitrosodi-n-butylamine
- N-Nitrosodiethanolamine
- N-Nitrosodi-n-propylamine
- 3-(N-Nitrosomethylamino)propionitrile
- N-Nitrosomethylethylamine
- N-Nitrosomethylvinylamine
- N-Nitrosomorpholine
- N-亞硝基哌啶
- N-Nitrosopyrrolidine
- N-Nitrososarcosine
- Ochratoxin A
- Oestrogen-progestogen therapy, postmenopausal
- Oil Orange SS
- 奧沙西泮
- 坡縷石 (attapulgite) (long fibres, >5微米)
- Panfuran S (containing dihydroxymethylfuratrizine)
- 非那吡啶
- 苯巴比妥
- 酚酞
- Phenoxybenzamine hydrochloride
- Phenyl glycidyl ether
- 苯妥英
- PhIP (2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine)
- Polychlorophenols and their sodium salts (mixed exposures)
- Ponceau MX
- Ponceau 3R
- 溴酸鉀
- Progestins
- Progestogen-only contraceptives
- 1,3-丙磺酸內酯
- Β-丙內酯
- 環氧丙烷
- 硫月尿酮(Propylthiouracil、PTU),抗甲狀腺藥物[12]
- 無線電波, such as, but not limited to, those associated with 流動電話 [13]
- 耐火陶瓷纖維
- 瑞德靈
- 黃樟素Safrole
- 日本血吸蟲 (infection with)
- Sodium orthophenyl phenol
- Special-purpose fibres such as E-glass and '475' glass fibres
- Sterigmatocystin
- 鏈脲佐菌素
- 苯乙烯
- Sulfallate
- 四氟乙烯
- 四硝基甲烷
- 硫乙酰胺
- 4,4'-Thiodianiline
- Thiouracil
- 二氧化鈦
- 二異氰酸甲苯(2,4-Toluene diiso-cyanate, 2,4-TDI)[14][15][16]
- 三氯氮芥 (Trimustine hydrochloride)
- Trp-P-1 (3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole)
- Trp-P-2 (3-Amino-1-methyl-5H-pyrido[4,3-b]indole)
- 台盼藍
- 烏拉莫司汀
- 五氧化二釩
- 乙酸乙烯酯
- 4-乙烯基環己烯
- 4-Vinylcyclohexene diepoxide
- 扎西他濱
- 齊多夫定(Zidovudine,AZT)
- 阿斯巴甜[17]
混合物
接觸場合
註釋
- 腳註
- ^1 Evaluated as a group.
- ^2 There is limited evidence in humans that coffee drinking is carcinogenic in the urinary bladder.
- ^3 There is some evidence of an inverse relationship between coffee drinking and cancer of the large bowel.
引用
- ^ Agents Classified by the IARC Monographs, Volumes 1–135. [2024-05-10]. (原始內容存檔於2024-05-02).
- ^ 談環境中的致癌物 (頁面存檔備份,存於互聯網檔案館) - 台北榮民總醫院 毒物科 楊振昌醫師
- ^ preamble to the IARC Monographs (頁面存檔備份,存於互聯網檔案館)pdf
- ^ 存档副本. [2014-11-24]. (原始內容存檔於2020-02-03).
- ^ 指定「危險物與有害物標示及通識規則 「危險物與有害物標示及通識規則」第二條第二款 」第二條第二款公告適用之 1,089 種危害物質名單 (PDF). [2014-11-24]. (原始內容存檔 (PDF)於2014-11-29).
- ^ [1][永久失效連結]
- ^ Bracken Fern - Bracken Fern or Brake Fern (Pteridium aquilinum) - Plants toxic to animals (頁面存檔備份,存於互聯網檔案館) - Veterinary Medicine library at U of Illinois
- ^ 存档副本. [2014-11-24]. (原始內容存檔於2019-07-28).
- ^ 存档副本 (PDF). [2014-11-24]. (原始內容存檔 (PDF)於2016-03-03).
- ^ 存档副本. [2014-09-20]. (原始內容存檔於2020-02-03).
- ^ 物質安全資料表 (頁面存檔備份,存於互聯網檔案館) - 勞動部勞動及職業安全衛生研究所
- ^ 存档副本. [2014-11-24]. (原始內容存檔於2014-11-18).
- ^ Press release No 208, 31 May 2011 (頁面存檔備份,存於互聯網檔案館), IARC classifies Radiofrequency Electromagnetic Fields as possibly carcinogenic to humans
- ^ 二異氰酸甲苯 (頁面存檔備份,存於互聯網檔案館) - 行政院毒災防救管理資訊系統
- ^ 2,4-二異氰酸甲苯健康危害 (頁面存檔備份,存於互聯網檔案館) - 國立陽明大學環境衛生研究所
- ^ 中華民國七十六年一月十五日,台北縣某工廠因二異氰酸甲苯(Toluene diisocyanate , TDI) (頁面存檔備份,存於互聯網檔案館) - 衛生福利部疾病管制署
- ^ 世卫组织:阿斯巴甜可能致癌. 聯合國新聞. 2023-07-13 [2023-07-14] (中文).
- ^ J, Wilbourn; C, Partensky; WG., Morgan. Printing Processes and Printing Inks, Carbon Black and Some Nitro Compounds. International Agency for Research on Cancer. 1996 [2023-10-31]. PMID 9148039. (原始內容存檔於2022-12-22).
- ^ Printing Processes and Printing Inks, Carbon Black and Some Nitro Compounds. IARC Publications Website. [2023-10-31]. (原始內容存檔於2023-10-31).
外部連結
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