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炔孕酮

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炔孕酮
臨床資料
商品名英語Drug nomenclatureProluton C, Pranone, others
其他名稱Ethinyltestosterone; Ethynyltestosterone; Pregneninolone; Anhydrohydroxyprogesterone; Etisteron; Pregnin; Ethindrone
給藥途徑口服給藥口腔黏膜吸收[1]
藥物類別英語Drug classProgestin; Progestogen; Androgen; Anabolic steroid
ATC碼
藥物動力學數據
代謝產物5α-雙氫炔孕酮英語5α-Dihydroethisterone[2]
識別資訊
  • (8R,9S,10R,13R,14S,17R)-17-Ethynyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
CAS號434-03-7  checkY
PubChem CID
ChemSpider
UNII
ChEBI
ChEMBL
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
ECHA InfoCard100.006.452 編輯維基數據鏈接
化學資訊
化學式C21H28O2
摩爾質量312.446 g/mol
3D模型(JSmol英語JSmol
  • C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@]4(C#C)O)C
  • InChI=1S/C21H28O2/c1-4-21(23)12-9-18-16-6-5-14-13-15(22)7-10-19(14,2)17(16)8-11-20(18,21)3/h1,13,16-18,23H,5-12H2,2-3H3/t16-,17+,18+,19+,20+,21+/m1/s1 checkY
  • Key:CHNXZKVNWQUJIB-CEGNMAFCSA-N checkY

炔孕酮(英語:Ethisterone),也有稱為乙炔睾酮(英語:ethinyltestosterone)、孕炔醇酮(英語:pregneninolone商品名:Proluton C 或 Pranone等)是一種黃體製劑藥物,過去被用於治療一些婦科疾病,但現在已不再使用[3][4][5]

參考文獻

  1. ^ University of California (1868-1952). Hospital Formulary and Compendium of Useful Information. University of California Press. 1952: 49–. GGKEY:2UAAZRZ5LN0. 
  2. ^ Lemus AE, Enríquez J, García GA, Grillasca I, Pérez-Palacios G. 5alpha-reduction of norethisterone enhances its binding affinity for androgen receptors but diminishes its androgenic potency. J. Steroid Biochem. Mol. Biol. 1997, 60 (1–2): 121–9. PMID 9182866. doi:10.1016/s0960-0760(96)00172-0. 
  3. ^ Swyer GI. Oral Hormonal Therapy for Menstrual Disorders. Br Med J. 1950, 1 (4654): 626–34. PMC 2037145可免費查閱. PMID 20787798. doi:10.1136/bmj.1.4654.626. 
  4. ^ Dr. Ian Morton; I.K. Morton; Judith M. Hall. Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. 31 October 1999: 115–. ISBN 978-0-7514-0499-9. 
  5. ^ 存档副本. [2019-06-24]. (原始內容存檔於2019-06-24).