阿巴康唑

阿巴康唑
臨床資料
ATC碼	未分配;
識別資訊
	IUPAC命名法 7-Chloro-3-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]quinazolin-4-one; ;
CAS號	187949-02-6
PubChem CID	208952;
ChemSpider	181045 ;
UNII	YDW24Y8IAB;
KEGG	D09702 ;
ChEMBL	ChEMBL298817 ;
CompTox Dashboard（英語：CompTox Chemicals Dashboard） (EPA)	DTXSID3058244 ;
ECHA InfoCard	100.170.829
化學資訊
化學式	C20H16ClF2N5O2
摩爾質量	431.83 g·mol−1
3D模型（JSmol（英語：JSmol））	交互式圖像;
	SMILES Fc1ccc(c(F)c1)[C@](O)([C@H](N3\C=N/c2cc(Cl)ccc2C3=O)C)Cn4ncnc4;
	InChI InChI=1S/C20H16ClF2N5O2/c1-12(28-11-25-18-6-13(21)2-4-15(18)19(28)29)20(30,8-27-10-24-9-26-27)16-5-3-14(22)7-17(16)23/h2-7,9-12,30H,8H2,1H3/t12-,20-/m1/s1 ; Key:UHIXWHUVLCAJQL-MPBGBICISA-N ;

阿巴康唑（INN：albaconazole；開發代號：UR-9825）是一種實驗性三唑類抗真菌藥。^[1]它具有潛在的廣譜活性，可能可以用於治療南美錐蟲病。^[2]^[3]它也被研究作為抗原蟲劑（英語：Antiprotozoal）。^[2]

參考資料

^ Albaconazole. Adis Insight. Springer Nature Switzerland AG.
^ ^2.0 ^2.1 Guedes, Paulo Marcos da Matta; Urbina, Julio A.; de Lana, Marta; Afonso, Luis C. C.; Veloso, Vanja M.; Tafuri, Washington L.; Machado-Coelho, George L. L.; Chiari, Egler; Bahia, Maria Terezinha. Activity of the New Triazole Derivative Albaconazole against Trypanosoma (Schizotrypanum) cruzi in Dog Hosts. Antimicrobial Agents and Chemotherapy. 2004-11, 48 (11). ISSN 0066-4804. PMID 15504854. doi:10.1128/AAC.48.11.4286-4292.2004.
^ Guillon, Rémi; Pagniez, Fabrice; Picot, Carine; Hédou, Damien; Tonnerre, Alain; Chosson, Elizabeth; Duflos, Muriel; Besson, Thierry; Logé, Cédric; Le Pape, Patrice. Discovery of a Novel Broad-Spectrum Antifungal Agent Derived from Albaconazole. ACS Medicinal Chemistry Letters. 2013-01-17, 4 (2). ISSN 1948-5875. PMC 4027234 . PMID 24900660. doi:10.1021/ml300429p.