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M34细胞

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维基百科，自由的百科全书

M34是一种人类皮肤黑色素瘤細胞系[1]，特点是其β2-微球蛋白基因发生了TTCT四碱基删失形成终止密码子造成了無義突變[2]，常用於生物医学研究[3]。

參考資料

  1. ^ Jiang, X; Zhou, J; Yuen, NK; Corless, CL; Heinrich, MC; Fletcher, JA; Demetri, GD; Widlund, HR; Fisher, DE; Hodi, FS. Imatinib targeting of KIT-mutant oncoprotein in melanoma.. Clinical cancer research : an official journal of the American Association for Cancer Research. 2008-12-01, 14 (23): 7726–32. PMID 19047099. doi:10.1158/1078-0432.CCR-08-1144. 
  2. ^ Fernández, MA; Ruiz-Cabello, F; Oliva, MR; Cabrera, T; Jimenez, P; López Nevot, MA; Garrido, F. Beta2-microglobulin gene mutation is not a common mechanism of HLA class I total loss in human tumors.. International journal of clinical & laboratory research. 2000, 30 (2): 87–92. PMID 11043502. doi:10.1007/BF02874164. 
  3. ^ Kucukkaraduman, B; Turk, C; Fallacara, AL; Isbilen, M; Senses, KM; Ayyildiz, ZO; Akbar, MW; Lotem, M; Botta, M; Gure, AO. Predictive Gene Signature for Pyrazolopyrimidine Derivative c-Src Inhibitor 10a Sensitivity in Melanoma Cells.. ACS medicinal chemistry letters. 2020-05-14, 11 (5): 928–932. PMID 32435407. doi:10.1021/acsmedchemlett.9b00679. 

外部連結

检索自“https://zh.wikipedia.org/w/index.php?title=M34细胞&oldid=83016591”