4-氟派醋甲酯

**4-氟派醋甲酯**
法律規範狀態
法律規範	加：Schedule III; 德：Legal; 英：PSA;
识别信息
	IUPAC命名法 Methyl 2-(4-fluorophenyl)-2-(piperidin-2-yl)acetate; ;
CAS号	1354631-33-6
PubChem CID	70876096;
ChemSpider	26350585 ;
UNII	TN2LV2C0X9;
化学信息
化学式	C14H18FNO2
摩尔质量	251.30 g·mol−1
3D模型（JSmol（英语：JSmol））	交互式图像;
熔点	222.0 °C（431.6 °F）
	SMILES FC1=CC=C(C=C1)C(C(=O)OC)C2CCCCN2;
	InChI InChI=1S/C14H18FNO2/c1-18-14(17)13(12-4-2-3-9-16-12)10-5-7-11(15)8-6-10/h5-8,12-13,16H,2-4,9H2,1H3; Key:XISBAJBPDVRSPG-UHFFFAOYSA-N;

4-氟派醋甲酯 （4-Fluoromethylphenidate），又称4-FMPH和4F-MPH，是一种兴奋剂，与哌醋甲酯相比，是一种效力更强的多巴胺再摄取抑制剂。^[2]^[3]^[4]

参考文献

^ The Drug Enforcement Administration's Special Testing and Research Laboratory Monograph (PDF). February 2017 [2023-10-01]. （原始内容存档 (PDF)于2022-06-18）.
^ Davies HM, Hopper DW, Hansen T, Liu Q, Childers SR. Synthesis of methylphenidate analogues and their binding affinities at dopamine and serotonin transport sites. Bioorganic & Medicinal Chemistry Letters. April 2004, 14 (7): 1799–802. PMID 15026075. doi:10.1016/j.bmcl.2003.12.097.
^ Misra M, Shi Q, Ye X, Gruszecka-Kowalik E, Bu W, Liu Z, et al. Quantitative structure-activity relationship studies of threo-methylphenidate analogs. Bioorganic & Medicinal Chemistry. October 2010, 18 (20): 7221–38. PMID 20846865. doi:10.1016/j.bmc.2010.08.034.
^ Singh S. Chemistry, design, and structure-activity relationship of cocaine antagonists. Chemical Reviews. March 2000, 100 (3): 925–1024. PMID 11749256. doi:10.1021/cr9700538.