3-羟酰辅酶A脱氢酶
3-羟酰辅酶A脱氢酶 | |||||||||
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3-羟酰辅酶A脱氢酶的结构(PDB 3had) | |||||||||
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识别码 | |||||||||
EC編號 | 1.1.1.35 | ||||||||
CAS号 | 9028-40-4 | ||||||||
数据库 | |||||||||
IntEnz | IntEnz浏览 | ||||||||
BRENDA | BRENDA入口 | ||||||||
ExPASy | NiceZyme浏览 | ||||||||
KEGG | KEGG入口 | ||||||||
MetaCyc | 代谢路径 | ||||||||
PRIAM | 概述 | ||||||||
PDB | RCSB PDB PDBj PDBe PDBsum | ||||||||
基因本体 | AmiGO / EGO | ||||||||
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3-羟酰辅酶A脱氢酶(英語:3-hydroxyacyl-CoA dehydrogenase,EC 1.1.1.35(页面存档备份,存于互联网档案馆))是一种以NAD+或NADP+为受体、作用于供体CH-OH基团上的氧化还原酶。这种酶能催化以下酶促反应:
3-羟酰辅酶A脱氢酶主要参与脂肪酸的代谢过程,如β-氧化的第三步等。
参考文献
- Hillmer P and Gottschalk G. Solubilization and partial characterisation of particulate dehydrogenases from Clostridium kluyveri. Biochim. Biophys. Acta. 1974, 334: 12–23.
- Lehninger AL, Greville GD. The enzymic oxidation of alpha- and 2-beta-hydroxybutyrate. Biochim. Biophys. Acta. 1953, 12 (1-2): 188–202. PMID 13115428. doi:10.1016/0006-3002(53)90138-3.* Stern JR. Crystalline beta-hydroxybutyryl dehydrogenase from pig heart. Biochim. Biophys. Acta. November 1957, 26 (2): 448–9. PMID 13499396. doi:10.1016/0006-3002(57)90040-9.
- Wakil SJ, Green DE, Mii S and Mahler HR. Studies on the fatty acid oxidizing system of animal tissues. VI. beta-Hydroxyacyl coenzyme A dehydrogenase. J. Biol. Chem. April 1954, 207 (2): 631–8. PMID 13163047.
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