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十一酸双氢睾酮

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十一酸双氢睾酮
臨床資料
其他名稱DHTU; 5α-Dihydrotestosterone 17β-undecanoate; Androstanolone undecanoate; Stanolone undecanoate; 5α-Androstan-17β-ol-3-one 17β-undecanoate; 3-Oxo-5α-androstan-17β-yl undecanoate
给药途径口服给药[1]
藥物類別英语Drug class雄激素同化類固醇雄激素酯
识别信息
  • [(5S,8R,9S,10S,13S,14S,17S)-10,13-Dimethyl-3-oxo-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl] undecanoate
CAS号6804-12-2  checkY
PubChem CID
ChemSpider
UNII
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C30H50O3
摩尔质量458.73 g·mol−1
3D模型(JSmol英语JSmol
  • CCCCCCCCCCC(=O)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CCC(=O)C4)C)C
  • InChI=1S/C30H50O3/c1-4-5-6-7-8-9-10-11-12-28(32)33-27-16-15-25-24-14-13-22-21-23(31)17-19-29(22,2)26(24)18-20-30(25,27)3/h22,24-27H,4-21H2,1-3H3/t22-,24-,25-,26-,27-,29-,30-/m0/s1
  • Key:AOQIVBOEDICQDB-KNWHVVHCSA-N

十一酸双氢睾酮(英語:Dihydrotestosterone undecanoate,缩写DHTU,或称为十一酸雄烷醇酮androstanolone undecanoate十一酸雄诺龙stanolone undecanoate)是一种有机化合物,分子式C30H50O3,是双氢睾酮的17β十一酸,可用作雄激素同化類固醇(AAS)药物[2][1][3][4]

参考文献

  1. ^ 1.0 1.1 Gooren LJ, van der Veen EA, van Kessel H, Harmsen-Louman W, Wiegel AR. Prolactin secretion in the human male is increased by endogenous oestrogens and decreased by exogenous/endogenous androgens. International Journal of Andrology. February 1984, 7 (1): 53–60. PMID 6715064. doi:10.1111/j.1365-2605.1984.tb00759.x. 
  2. ^ Swerdloff RS, Dudley RE, Page ST, Wang C, Salameh WA. Dihydrotestosterone: Biochemistry, Physiology, and Clinical Implications of Elevated Blood Levels. Endocrine Reviews. June 2017, 38 (3): 220–254. PMC 6459338可免费查阅. PMID 28472278. doi:10.1210/er.2016-1067. 
  3. ^ Gooren LJ, van der Veen EA, van Kessel H, Harmsen-Louman W, Wiegel AR. Androgens in the feedback regulation of gonadotropin secretion in men: effects of administration of dihydrotestosterone to eugonadal and agonadal subjects and of spironolactone to eugonadal subjects. Andrologia. 1984, 16 (4): 289–298. PMID 6433746. S2CID 32546312. doi:10.1111/j.1439-0272.1984.tb00286.x可免费查阅. 
  4. ^ Gooren LJ. Human male sexual functions do not require aromatization of testosterone: a study using tamoxifen, testolactone, and dihydrotestosterone. Archives of Sexual Behavior. December 1985, 14 (6): 539–548. PMID 4084053. S2CID 23059918. doi:10.1007/BF01541754. 

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