十一酸双氢睾酮
臨床資料 | |
---|---|
其他名稱 | DHTU; 5α-Dihydrotestosterone 17β-undecanoate; Androstanolone undecanoate; Stanolone undecanoate; 5α-Androstan-17β-ol-3-one 17β-undecanoate; 3-Oxo-5α-androstan-17β-yl undecanoate |
给药途径 | 口服给药[1] |
藥物類別 | 雄激素、同化類固醇、雄激素酯 |
识别信息 | |
| |
CAS号 | 6804-12-2 |
PubChem CID | |
ChemSpider | |
UNII | |
CompTox Dashboard (EPA) | |
化学信息 | |
化学式 | C30H50O3 |
摩尔质量 | 458.73 g·mol−1 |
3D模型(JSmol) | |
| |
|
十一酸双氢睾酮(英語:Dihydrotestosterone undecanoate,缩写DHTU,或称为十一酸雄烷醇酮,androstanolone undecanoate,十一酸雄诺龙,stanolone undecanoate)是一种有机化合物,分子式C30H50O3,是双氢睾酮的17β十一酸酯,可用作雄激素和同化類固醇(AAS)药物。[2][1][3][4]
参考文献
- ^ 1.0 1.1 Gooren LJ, van der Veen EA, van Kessel H, Harmsen-Louman W, Wiegel AR. Prolactin secretion in the human male is increased by endogenous oestrogens and decreased by exogenous/endogenous androgens. International Journal of Andrology. February 1984, 7 (1): 53–60. PMID 6715064. doi:10.1111/j.1365-2605.1984.tb00759.x.
- ^ Swerdloff RS, Dudley RE, Page ST, Wang C, Salameh WA. Dihydrotestosterone: Biochemistry, Physiology, and Clinical Implications of Elevated Blood Levels. Endocrine Reviews. June 2017, 38 (3): 220–254. PMC 6459338 . PMID 28472278. doi:10.1210/er.2016-1067.
- ^ Gooren LJ, van der Veen EA, van Kessel H, Harmsen-Louman W, Wiegel AR. Androgens in the feedback regulation of gonadotropin secretion in men: effects of administration of dihydrotestosterone to eugonadal and agonadal subjects and of spironolactone to eugonadal subjects. Andrologia. 1984, 16 (4): 289–298. PMID 6433746. S2CID 32546312. doi:10.1111/j.1439-0272.1984.tb00286.x .
- ^ Gooren LJ. Human male sexual functions do not require aromatization of testosterone: a study using tamoxifen, testolactone, and dihydrotestosterone. Archives of Sexual Behavior. December 1985, 14 (6): 539–548. PMID 4084053. S2CID 23059918. doi:10.1007/BF01541754.