苯呋洛爾
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臨床資料 | |
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商品名 | Benfuran, Bentos, Betaclar, Glauconex |
AHFS/Drugs.com | 國際藥品名稱 |
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CAS號 | 39552-01-7 ![]() |
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CompTox Dashboard (EPA) | |
化學資訊 | |
化學式 | C16H21NO4 |
摩爾質量 | 291.35 g·mol−1 |
3D模型(JSmol) | |
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苯呋洛爾(INN:Befunolol)是一種具有內在擬交感活性的β受體阻滯劑,用於治療開角型青光眼。[1]它還充當β-腎上腺素能受體部分激動劑。[2][3]苯呋洛爾於1983年由科研藥化工(Kakenyaku Kako)在日本推出,商品名為Bentos。[4]
參考資料
- ^ Reichl S, Müller-Goymann CC. The use of a porcine organotypic cornea construct for permeation studies from formulations containing befunolol hydrochloride. International Journal of Pharmaceutics. January 2003, 250 (1): 191–201. PMID 12480285. doi:10.1016/S0378-5173(02)00541-0.
- ^ Koike K, Takayanagi I. A beta-adrenergic partial agonist (befunolol) discriminates two different affinity sites. Japanese Journal of Pharmacology. October 1986, 42 (2): 325–8. PMID 2879061. doi:10.1254/jjp.42.325
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- ^ Takayanagi I, Koike K. A beta-adrenoceptor blocking agent, befunolol as a partial agonist in isolated organs. General Pharmacology. January 1985, 16 (3): 265–7. PMID 2862092. doi:10.1016/0306-3623(85)90080-1.
- ^ Pharmaceutical Manufacturing Encyclopedia 3rd revised. Norwich, N.Y.: William Andrew Publishing. January 14, 2008: 542. ISBN 978-0815515265.
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